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Merkels disks are located superficially in the dermis of skin at the base of the epidermis and lie adjacent to meissners corpuscles and sweat glands.
Merkel disc in skin. Functionally sa1 responses in fingertips and whisker hair follicles are essential for tactile discrimination of an objects texture shape and other. Merkel cell carcinoma most often develops in older people. Merkel cell carcinoma merkel cell carcinoma is a rare type of skin cancer that usually appears as a flesh colored or bluish red nodule often on your face head or neck. They adapt slowly to pressure and therefore record the sustained presence of pressure on the skin.
Merkel nerve endings are mechanoreceptors a type of sensory receptor that are found in the basal epidermis and hair follicles. Tactile stimuli to merkel discs in the touch domes of the skin and whisker hair follicles result in slowly adapting type 1 sa1 responses the characteristic ab afferent impulses for tactile encoding 2 5. Each ending consists of a merkel cell in close apposition with an enlarged nerve terminal. Merkel discs have high tactile acuity and are very sensitive to skin indentation pressure hair movement and other tactile stimuli.
That is the hairless skin found on the palms and fingers the soles of the feet and the lips of humans and other primates. These receptors respond to indentation of the skin. Merkel cell carcinoma is also called neuroendocrine carcinoma of the skin. They are nerve endings and provide information on mechanical pressure position and deep static touch features such as shapes and edges.
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