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They are abundant in highly sensitive skin like that of the fingertips in humans and make synaptic contacts with somatosensory afferent nerve fibers.
Merkel cells are found in the. Merkel cells are found at the base of the outermost layer of your skin epidermis. Merkel cells can be found in the stratum basale of the palms soles oral and genital mucosa and nail bed. Though it has been reported that merkel cells are derived from neural crest cells more recent experiments in mammals have indicated that they are in fact epithelia. Merkel cells also known as merkel ranvier cells or tactile epithelial cells are oval shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates.
Researchers recently discovered that a common virus plays a role in causing most cases of merkel cell carcinoma. Merkel cells normally exist in the bottom basal layer of the epidermis about 01 mm from skins surface. Found directly above the basement membrane they contain intracytoplasmic dense core neurosecretory like granules as well as neurofilaments and keratin. Merkel cell carcinoma mcc is a rare neuroendocrine tumor of the skin.
Merkel cells are connected to nerves signaling touch sensation as touch receptors mcc was named after merkel cells due to the similar microscopic features. Merkel cells are connected to the nerve endings in the skin that are responsible for the sense of touch. Merkel cells are found in the epidermis epidermis the outermost layer of the two main layers that make up the skin the dermis is the deeper layer. However recent research suggests that it is unlikely that mcc originates directly from normal merkel cells.
Merkel cells are located deep in the top layer of skin. A merkel cell is a touch receptor found in the skin.
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