Eplerenone Structure

Classed as a selective aldosterone receptor antagonist it is similar to the diuretic spironolactone though it is much more selective for the mineralocorticoid receptor in comparison and is specifically marketed. You may not be able to take eplerenone if you have severe kidney disease high potassium levels in your blood or type 2 diabetes with increased levels of albumin a protein in your urine. These are steroid lactones with a structure based on the spironolactone skeleton.
eplerenone structure

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Eplerenone is in a class of medications called mineralocorticoid receptor antagonists.

Eplerenone structure. The structural formula of eplerenone is represented below. Eplerenone inspra is an aldosterone receptor blocker which is an antihypertensive used to treat congestive heart failure after a heart attack and is also used to treat high blood pressure hypertension. View chapter purchase book read full chapter. Talk with the doctor.

Eplerenone is chemically described as pregn 4 ene 721 dicarboxylic acid 911 epoxy 17 hydroxy 3oxo g lactone methyl ester 7a11a17a. Eplerenone ep impurity c. The two aldosterone antagonists on the market that are commonly used for the treatment of hypertension htn andor heart failure hf due to left ventricular systolic dysfunction are eplerenone inspra and spironolactone aldactone12 in addition to these indications spironolactone is available generically is less prone to drug interactions and is also used in the management of primary. Eplerenone was designed after the structure of the aldosterone receptor had been mapped and is therefore more specific for this receptor.

If you have an allergy to eplerenone or any other part of eplerenone. It is used to help heart function after a heart attack. High blood pressure is a common condition and when not treated can cause damage to the brain heart blood vessels kidneys and other parts of the body. It works by blocking the action of aldosterone a natural substance in the body that raises blood pressure.

Eplerenone also known as inspra or epoxymexrenone belongs to the class of organic compounds known as spironolactones and derivatives. 95716 70 4 7a17a 17 hydroxy 3 oxo pregna 4911 diene 721 dicarboxylicacid g lactone methyl ester. What do i need to tell my doctor before i take eplerenone. It may be given to you for other reasons.

Its empirical formula is c 24 h 30 o 6 and it has a molecular weight of 41450. Drugs a z pill identifier supplements symptom checker diseases dictionary media. Eplerenone sold under the brand name inspra is a steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure and high blood pressure particularly for patients with resistant hypertension due to elevated aldosterone. It is used to treat high blood pressure.

Tell your doctor about all your current medicines and any you start or stop using.

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