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Indications dose contra indications side effects interactions cautions warnings and other safety information for eplerenone.
Eplerenone site of action. It is used to help heart function after a heart attack. It works by blocking the action of aldosterone a natural substance in the body that raises blood pressure. Eplerenone is a selective aldosterone receptor antagonist. Eplerenone sold under the brand name inspra is a steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure and high blood pressure particularly for patients with resistant hypertension due to elevated aldosterone.
This leads to a decrease in blood pressure. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone a component of the renin angiotensin aldosterone system raas. High blood pressure is a common condition and when not treated can cause damage to the brain heart blood vessels kidneys and other parts of the body. A class of drugs is a group of medications that work in a similar way.
Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone thereby decreasing sodium resorption and subsequently increasing water outflow. Talk with the doctor. Classed as a selective aldosterone receptor antagonist it is similar to the diuretic spironolactone though it is much more selective for the mineralocorticoid receptor in comparison and is specifically marketed. Eplerenone is a competitive antagonist of aldosterone at mineralocorticoid receptors.
Eplerenone is a selective mineralocorticoid receptor antagonist and as such is generally well tolerated with most frequent adverse event being hyperkalemia while the sexual adverse events such as gynecomastia and vaginal bleeding such as in spironolactone are limited with this agent 28 r 29 r. It may be given to you for other reasons. Eplerenone belongs to a class of drugs called aldosterone antagonists. If you have an allergy to eplerenone or any other part of eplerenone.
Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone a component of the renin angiotensin aldosterone system raas. It is used to treat high blood pressure. What do i need to tell my doctor before i take eplerenone.
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